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CHARM Developmental Awards Program - Full Application Submission

PRINCIPAL INVESTIGATOR INFORMATION

(Refer to the "Applicant Eligibility" section of the RFA before completing and submitting an application.)

Please enter today's date:

M-D-Y

Which CHARM Developmental Award are you applying for?

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Pilot Award

Scholar Award

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Last Name

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First Name

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Middle Name or Initial

Institution

Primary Department

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Division (if applicable)

Degree(s)
Check all that apply

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MD PhD Other

If you hold another degree, please specify

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NIH eRA Username

Email Address

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Phone number(s) where you can easily be reached for clarifications

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TYPE OF APPLICATION (Note: Only first submission and first re-submission are allowable)
This proposal is:

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New application (was never submitted to any UM internal grant mechanism (e.g., CHARM, CTSI, CFAR, Cancer Center, etc.)

Resubmission (submitted but not funded by a UM internal grant mechanism [e.g., CHARM, CTSI, CFAR, Cancer Center, etc.])

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Please indicate which UM internal grant mechanism this a resubmission from?

CHARM

CTSI

CFAR

Cancer Center

Other

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Other:

Please upload the "Introduction" section with the following specifics:

1. Summarize substantial additions, deletions, and changes to the application
2. Do not markup changes within application attachments (e.g., do not highlight, color, bold or italicize changes)
3. Respond to the issues and criticism raised in the summary statement
4. Limit it to one page or less in length

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Project Title

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Is this an implementation science project?

Implementation science is research on equitably implementing and disseminating evidence-based interventions (EBIs) to reach communities that could most benefit.

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Yes

Unsure

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CO-INVESTIGATORS, OTHER SIGNIFICANT CONTRIBUTORS, AND MENTORS

Complete this "Collaborators Table" document which is also available on the CHARM website under "Forms and Instructions" with information on the Co-Investigators, Other Significant Contributors, and Mentors. Do not list research staff (coordinators, research assistants, etc.). The applicant requires an NIH biosketch for each individual listed on the collaboration table.

A Co-Investigator is someone with a key role in the project.

Other Significant Contributors are typically investigators contributing a key element/expertise to the project but not necessarily a mentor.

Mentors are typically senior investigators responsible for advising the PI during the project. Applications submitted by junior investigators at assistant professor level, and post-doctoral fellows require a mentor to be listed on their project.

Note: Applicants that are from other institutions other than Univeristy of Miami, Florida International University, Nova Southeastern University, University of Central Florida and Florida State University will need a mentor or Co-Investigator from CHARM.

File Name: Last name_collaborators_typeofaward_year

ex. Smith_collaborators_pilot_2024

ex. Alvarez_collaborators_scholar_2024

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PUBLIC HEALTH RELEVANCE

Using no more than two or three sentences, describe the relevance of this research to public health. In this section, be succinct and use plain language that can be understood by a general, lay audience. (LIMIT 3 sentences-lay language)

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PROJECT SUMMARY/ABSTRACT

This section is meant to serve as a succinct and accurate description of the proposed work when separated from the application. State the application's broad, long-term objectives and specific aims, making reference to the health relatedness of the project. Describe concisely the research design and methods for achieving the stated goals. This section should be informative to other persons working in the same or related fields and insofar as possible understandable to a scientifically or technically literate reader.

Format: LIMIT 30 lines of text, Arial 11 point font, single-spacing, 0.5" margins

File Name: Last Name_abstract_typeofaward_year
ex. Smith_abstract_pilot_2024

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SPECIFIC AIMS

• State concisely the goals of the proposed research and summarize the expected outcome(s), including the impact that the results of the proposed research will exert on the field(s) involved.

• List succinctly the specific objectives of the research proposed (e.g., to test a stated hypothesis, create a novel design, solve a specific problem, challenge an existing paradigm or clinical practice, address a critical barrier to progress in the field, or develop new technology).

Format: LIMIT 1 PAGE, Arial 11 point font, single-spacing, 0.5" all margins

File Name: Last Name_aims_typeofaward_year
ex. Smith_aims_pilot_2024

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RESEARCH STRATEGY

Address Significance, Innovation and Approach. Include a timeline for the project.

Significance:
• Explain the importance of the problem or critical barrier to progress that the proposed project addresses.
• Describe the scientific premise for the proposed project, including consideration of the strengths and weaknesses of published research or preliminary data crucial to the support of your application.
• Explain how the proposed project will improve scientific knowledge, technical capability, and/or clinical practice in one or more broad fields.
• Include information on preliminary studies. Discuss the PI's preliminary studies, data, and or experience pertinent to this application.

Innovation:
• Explain how the application challenges and seeks to shift current research or clinical practice paradigms.
• Describe any novel theoretical concepts, approaches or methodologies, instrumentation or intervention(s) to be developed or used, and any advantage over existing methodologies, instrumentation, or intervention(s).
• Explain any refinements, improvements, or new applications of theoretical concepts, approaches or methodologies, instrumentation, or interventions.

Approach:
• Describe the overall strategy, methodology, and analyses to be used to accomplish the specific aims of the project. Describe the experimental design and methods proposed and how they will achieve robust and unbiased results. Include how the data will be collected, analyzed, and interpreted as well as any resource sharing plans as appropriate.
• Discuss potential problems, alternative strategies, and benchmarks for success anticipated to achieve the aims.
• Describe any strategy to establish feasibility, and address the management of any high risk aspects of the proposed work.
• Explain how relevant biological variables, such as sex, are factored into research designs and analyses.

Format: LIMIT to 6 pages (including timeline), Arial 11 point font, single-spacing, 0.5" margins

File Name: Last Name_Strategy_typeofaward_year
ex. Smith_Strategy_pilot_2024

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COMMUNITY ENGAGEMENT

Provide a: 1) list of proposed community partner(s) or agency(ies) AND 2) paragraph (500 word limit) explaining a) how the project will engage the community, b) the role of the proposed community partner(s) or agency(ies), c) how the findings may impact the community, AND d) what compensation will be offered to the community partner.

Please note: A Community Partner is a community organization outside of academic institutions involved with services and activities related to HIV and mental health such as advocacy, community support services, or any community work related to ending the HIV epidemic in South Florida and beyond.

The chosen community partner/agency should be engaged in the design and execution of the project as well as in the interpretation and publication of findings. Community partners can be engaged at varying levels from a consultative role to community-based participatory research.

Format: Include list (no word limit) and paragraph (400 word limit), Arial 11 point font, single-spacing, 0.5" margins

File name: Last name__Community_typeofaward_year
ex. Smith_community_pilot_2024

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CAREER DEVELOPMENT GOALS, FUTURE FUNDING, and MENTORSHIP PLAN

• Describe how this project is important to your career goals. Explain the direction of your research and your long-term goals,
• Explain how the results from this project will lay the foundation for extramural funding. Indicate a project timeline for submitting extramural grant application(s). Specify which type of grant you expect to submit.

Format: LIMIT 3 pages, Arial 11 point font, single-spacing, 0.5" all margins.

File Name: Last Name_Goals_Funding_typeofaward_year
ex. Smith_goals_funding_pilot_2024

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BIBLIOGRAPHY & REFERENCES CITED

Do not include any visuals or any information that is not a cited reference.

Format: No page limit; Arial 11 point font, single-spacing, 0.5" all margins.

File Name Format: Last Name_References_typeofaward_year
ex. Smith_references_pilot_2024

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CHARM USAGE

All applicants are required to use the CHARM resources pre-submission and post-award. To this end, a) list and describe which Core(s) were consulted or resource(s) used in preparing this application AND b) list and describe which Core(s) may be consulted or resource(s) used post-award. Refer to the "About the Center" and "Research Support" sections on the CHARM website for information on CHARM Cores and resources.

Format: No word/page limit; Arial 11 point font, single-spacing, 0.5" all margins.

File Name: Last Name_Center usage_typeofaward_year
ex. Smith_centerusage_pilot_2024_

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BUDGET & BUDGET JUSTIFICATION

Awards will be of up to $45,000 (direct costs only) for a one-year period (06/01/2024 - 05/31/2025; the period may start before or after 06/2024). Applicants must use the PHS 398 Form Page 4 (Detailed Budget for Initial Budget Period) to submit their budget. Download the form from the linked NIH site. The University of Miami's indirect cost rate must be factored in along with the applicant's institutional indirect cost rate.

Expenses should be restricted to personnel, research supplies, cost for subject participation, test supplies and technical support. Applicants must provide a budget justification for each person, including a detailed description of the role for each investigator considering the proposed effort, and item listed in the budget. Fringe rates prescribed by your institution should be used. Names and positions of all personnel must be individually listed and the percentage of time to be devoted to the project by each person should be noted. If an individual is being listed with effort but no salary support, they typically should be listed as mentor or other significant contributor. If an individual has not yet been hired, please list as "TBD."

Applicants may be asked to revise the proposed budget and corresponding justification before funding consideration.

Use the "Budget_Template" alo available on the CHARM website under "Forms and Instructions". BOTH the budget AND budget justification should be uploaded.

File Name: Last name__Budget_typeofaward_year

ex. Smith_budget_pilot_2024

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BIOSKETCHES

Biosketches are required for the PI, Co-Investigators, Other Significant Contributors and Mentors. Please use NIH style Biosketch format. You can find a "Biosketch template" available on the CHARM website under "Forms and Instructions" and upload as ONE PDF. Instructions on completing NIH biosketches are available here.

File Name: Last Name__Bioskectches_typeofaward_year

ex. Smith_biosketches_pilot_2024

Format: 5-page limit per Biosketch

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LETTERS OF SUPPORT AND COMMITMENT

• Community Partner/Agency: A letter of support from your community partner or agency is REQUIRED and should clearly spell out their roles in the project. The award application should contain a signed and dated letter from each community partner or agency that lists the contributions and expresses their commitment to the project.

• Consultants: On agency letterhead, Letters should include rate/charge for consulting services. If community partners or agencies will serve as consultants and be compensated, their letter of support should also include their rate/charge for consulting services.

• Mentor: Early career faculty and post-doctoral fellows are REQUIRED to name a mentor and include a letter of support. The letter should reflect support from the mentor and detail exactly how the mentor intends to support the pilot applicant. Applicants from Florida International University, Nova Southeastern University, and Florida State University will need a mentor or Co-Investigator from CHARM.

• Department Chair: For post-doctoral fellows, a letter from the Department Chair is required. The letter should indicate support for the application and a potential research/faculty appointment at the completion of the post-doctoral fellowship.

Upload all the letters in ONE PDF

File Name: Last Name__LOS_typeofaward_year
ex. Smith_LOS_pilot_2024

* must provide value

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Consider that all UM faculty are potential reviewers.

You may name any potential reviewers who you believe could not provide an impartial review and request they not review your application. The Review Committee will consider this request but is not required to accommodate it. You may include a justification for your selection (optional).

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Please provide any recommendations for reviewers. They should not be current collaborators or mentors. If they are external to UM, please provide the institutional affiliation and email address.

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